Multiomics technology refers to the application of more than one Omics technology (genomics, transcriptomics, proteomics, metabolomics, etc.) to the same set of studied subjects, generating multiple types of data that can be cross investigated to obtain complementary information among different biomolecules. The multiomics approach can explore phenotypes and underlying mechanisms of complex life systems from a systemic point of view, providing comprehensive interpretation of the studied questions. The application of multiomics approach in disease research would provide more complete and new perspective into specific molecular changes during different stages of disease development, link biomolecules to distinct phenotypes, and promote the discovery of new clinical biomarkers and drug targets.

Mass spectrometry is a core technology of multiomics research. Calbra is deeply engaged in multiomics research and applications with focus on proteomics and metabolomics studies. The multiomics platform developed at Calibra is CalOmics. The CalOmics nontargeted metabolomics platform integrates proprietary reference standard library covering thousands of compounds, patented laboratory information management system (LIMS), industrial-level quality control system, and manual curation of software generated results to realize reliable metabolite identification and accurate quantitative analysis. The CalOmics proteomics platform has dozens of characteristic protein reference databases on common clinical body fluids and tissue samples, covering more than 85% of the composition of human proteins. The platform can detect large number of proteins from low volume of body fluid samples using advanced cloud data analysis platform with high-throughput data processing capability.